Increased ex vivo cell death of central memory CD4 T cells in treated HIV infected individuals with unsatisfactory immune recovery

BACKGROUND: High levels of ex vivo CD4 T-cell death and the accumulation of highly differentiated and/or immunosenescent T cells have been associated with poor CD4 T-cell recovery in treated HIV-infected individuals. However, the relationship between cell death and T-cell differentiation is still un...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Massanella, Marta, Gómez-Mora, Elisabet, Carrillo, Jorge, Curriu, Marta, Ouchi, Dan, Puig, Jordi, Negredo, Eugènia, Cabrera, Cecilia, Clotet, Bonaventura, Blanco, Julià
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504072/
https://ncbi.nlm.nih.gov/pubmed/26183947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0601-2
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