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Cell type-specific Nrf2 expression in multiple sclerosis lesions

Oxidative injury appears to play a major role in the propagation of demyelination and neurodegeneration in multiple sclerosis (MS). It has been suggested that endogenous anti-oxidant defense mechanisms within MS lesions are insufficient to prevent spreading of damage. Thus, current therapeutic appro...

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Détails bibliographiques
Publié dans:Acta Neuropathol
Auteurs principaux: Licht-Mayer, Simon, Wimmer, Isabella, Traffehn, Sarah, Metz, Imke, Brück, Wolfgang, Bauer, Jan, Bradl, Monika, Lassmann, Hans
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503875/
https://ncbi.nlm.nih.gov/pubmed/26087903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1452-x
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