Pro-Inflammatory Cytokine IL-1β Up-Regulates CXC Chemokine Receptor 4 via Notch and ERK Signaling Pathways in Tongue Squamous Cell Carcinoma

Chronic inflammation contributes to tumor development through the induction of oncogenic mutations, genomic instability, early tumor promotion, and enhanced angiogenesis. Here, we report that IL-1 receptor 1 (IL-1R1) was expressed in 40 of 41 human tongue squamous cell carcinomas (TSCC). IL-1β up-re...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sun, Yi, Zhu, Demao, Wang, Guihua, Wang, Di, Zhou, Huashan, Liu, Xueting, Jiang, Manli, Liao, Lingjuan, Zhou, Zhiguang, Hu, Jinyue
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503771/
https://ncbi.nlm.nih.gov/pubmed/26176534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132677
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