Humanized Chronic Graft-versus-Host Disease in NOD-SCID il2rγ-/- (NSG) Mice with G-CSF-Mobilized Peripheral Blood Mononuclear Cells following Cyclophosphamide and Total Body Irradiation

Chronic graft-versus-host disease (cGvHD) is the major source of late phase morbidity and mortality after allogeneic hematopoietic stem cell transplantation. Humanized acute GvHD (aGvHD) in vivo models using NOD-SCID il2rγ-/- (NSG) mice are well described and are important tools for investigating pa...

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Foilsithe in:PLoS One
Main Authors: Fujii, Hisaki, Luo, Zhi-Juan, Kim, Hye Jin, Newbigging, Susan, Gassas, Adam, Keating, Armand, Egeler, R. Maarten
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503770/
https://ncbi.nlm.nih.gov/pubmed/26176698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133216
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