Unexpected Inflammatory Effects of Intravaginal Gels (Universal Placebo Gel and Nonoxynol-9) on the Upper Female Reproductive Tract: A Randomized Crossover Study

Intravaginal anti-HIV microbicides could provide women with a self-controlled means for HIV prevention, but results from clinical trials have been largely disappointing. We postulated that unrecognized effects of intravaginal gels on the upper female reproductive tract might contribute to the lower-...

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Pubblicato in:PLoS One
Autori principali: Smith-McCune, Karen, Chen, Joseph C., Greenblatt, Ruth M., Shanmugasundaram, Uma, Shacklett, Barbara L., Hilton, Joan F., Johnson, Brittni, Irwin, Juan C., Giudice, Linda C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503751/
https://ncbi.nlm.nih.gov/pubmed/26177352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129769
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