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The SMC Loader Scc2 Promotes ncRNA Biogenesis and Translational Fidelity

The Scc2-Scc4 complex is essential for loading the cohesin complex onto DNA. Cohesin has important roles in chromosome segregation, DSB repair, and chromosome condensation. Here we report that Scc2 is important for gene expression in budding yeast. Scc2 and the transcriptional regulator Paf1 collabo...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Zakari, Musinu, Trimble Ross, Rhonda, Peak, Allison, Blanchette, Marco, Seidel, Chris, Gerton, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503661/
https://ncbi.nlm.nih.gov/pubmed/26176819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005308
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