Loss of Allograft Inflammatory Factor-1 Ameliorates Experimental Autoimmune Encephalomyelitis by Limiting Encephalitogenic CD4 T-Cell Expansion

Experimental autoimmune encephalomyelitis (EAE), an animal model of human multiple sclerosis (MS), is mediated by myelin-specific autoreactive T cells that cause inflammation and demyelination in the central nervous system (CNS), with significant contributions from activated microglia and macrophage...

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Publicado no:Mol Med
Main Authors: Chinnasamy, Prameladevi, Lutz, Sarah E, Riascos-Bernal, Dario F, Jeganathan, Venkatesh, Casimiro, Isabel, Brosnan, Celia F, Sibinga, Nicholas ES
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503655/
https://ncbi.nlm.nih.gov/pubmed/25569805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00264
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