Guggulsterone and bexarotene induce secretion of exosome-associated breast cancer resistance protein and reduce doxorubicin resistance in MDA-MB-231 cells

Many breast cancer cells acquire multidrug resistance (MDR) mediated by ABC transporters such as breast cancer resistance protein (BCRP/ABCG2). Here we show that incubation of human breast cancer MDA-MB-231 cells with farnesoid X receptor antagonist guggulsterone (gug) and retinoid X receptor agonis...

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Bibliografske podrobnosti
izdano v:Int J Cancer
Main Authors: Kong, Ji Na, He, Qian, Wang, Guanghu, Dasgupta, Somsankar, Dinkins, Michael B., Zhu, Gu, Kim, Austin, Spassieva, Stefka, Bieberich, Erhard
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503537/
https://ncbi.nlm.nih.gov/pubmed/25833198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.29542
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