Dose-Independent ADME Properties and Tentative Identification of Metabolites of α-Mangostin from Garcinia mangostana in Mice by Automated Microsampling and UPLC-MS/MS Methods

The information about a marker compound's pharmacokinetics in herbal products including the characteristics of absorption, distribution, metabolism, excretion (ADME) is closely related to the efficacy/toxicity. Also dose range and administration route are critical factors to determine the ADME...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Han, Seung Yon, You, Byoung Hoon, Kim, Yu Chul, Chin, Young-Won, Choi, Young Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503439/
https://ncbi.nlm.nih.gov/pubmed/26176540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131587
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