Impact of MS genetic loci on familial aggregation, clinical phenotype, and disease prediction

OBJECTIVE: To investigate the role of known multiple sclerosis (MS)-associated genetic variants in MS familial aggregation, clinical expression, and accuracy of disease prediction in sporadic and familial cases. METHODS: A total of 1,443 consecutive patients were screened for MS and familial autoimm...

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Detalhes bibliográficos
Publicado no:Neurol Neuroimmunol Neuroinflamm
Main Authors: Esposito, Federica, Guaschino, Clara, Sorosina, Melissa, Clarelli, Ferdinando, Ferre', Laura, Mascia, Elisabetta, Santoro, Silvia, Pagnesi, Matteo, Radaelli, Marta, Colombo, Bruno, Moiola, Lucia, Rodegher, Mariaemma, Stupka, Elia, Martinelli, Vittorio, Comi, Giancarlo, Martinelli Boneschi, Filippo
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503410/
https://ncbi.nlm.nih.gov/pubmed/26185776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000129
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