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Delta Inulin Adjuvant Enhances Plasmablast Generation, Expression of Activation-Induced Cytidine Deaminase and B-Cell Affinity Maturation in Human Subjects Receiving Seasonal Influenza Vaccine

There is a major need for new adjuvants to improve the efficacy of seasonal and pandemic influenza vaccines. Advax is a novel polysaccharide adjuvant based on delta inulin that has been shown to enhance the immunogenicity of influenza vaccine in animal models and human clinical trials. To better und...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Li, Lei, Honda-Okubo, Yoshikazu, Li, Connie, Sajkov, Dimitar, Petrovsky, Nikolai
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503308/
https://ncbi.nlm.nih.gov/pubmed/26177480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132003
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