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Single versus parallel pathways of protein folding and fractional formation of structure in the transition state.

Protein engineering and kinetic experiments indicate that some regions of proteins have partially formed structure in the transition state for protein folding. A crucial question is whether there is a genuine single transition state that has interactions that are weakened in those regions or there a...

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Detalhes bibliográficos
Main Authors: Fersht, A R, Itzhaki, L S, elMasry, N F, Matthews, J M, Otzen, D E
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC45033/
https://ncbi.nlm.nih.gov/pubmed/7937968
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