Loading...

Matrine inhibits IL-1β-induced expression of matrix metalloproteinases by suppressing the activation of MAPK and NF-κB in human chondrocytes in vitro

Interleukin (IL)-1β plays an important role in promoting osteoarthritis (OA) lesions by inducing chondrocytes to secrete matrix metalloproteinases (MMPs), which degrade the extracellular matrix and facilitate chondrocyte apoptosis. Matrine was shown to exert anti-inflammatory effects. However, the r...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Int J Clin Exp Pathol
Main Authors: Lu, Shijin, Xiao, Xungang, Cheng, Minghua
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4503038/
https://ncbi.nlm.nih.gov/pubmed/26191166
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!