A comparative study of the localization and membrane topology of members of the RIFIN, STEVOR and PfMC-2TM protein families in Plasmodium falciparum-infected erythrocytes

BACKGROUND: Variant surface antigens (VSA) exposed on the membrane of Plasmodium falciparum infected erythrocytes mediate immune evasion and are important pathogenicity factors in malaria disease. In addition to the well-studied PfEMP1, the small VSA families RIFIN, STEVOR and PfMC-2TM are assumed t...

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Udgivet i:Malar J
Main Authors: Bachmann, Anna, Scholz, Judith Anna Marie, Janßen, Marthe, Klinkert, Mo-Quen, Tannich, Egbert, Bruchhaus, Iris, Petter, Michaela
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502930/
https://ncbi.nlm.nih.gov/pubmed/26173856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-0784-2
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