Loading...

Specific loss of apoptotic but not cell-cycle arrest function in a human tumor derived p53 mutant.

The p53 tumor-suppressor gene product is frequently inactivated in malignancies by point mutation. Although most tumor-derived p53 mutants show loss of sequence specific transcriptional activation, some mutants have been identified which retain this activity. One such mutant, p53175P, is defective f...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Rowan, S, Ludwig, R L, Haupt, Y, Bates, S, Lu, X, Oren, M, Vousden, K H
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC450281/
https://ncbi.nlm.nih.gov/pubmed/8631304
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!