SUMO1 promotes Aβ production via the modulation of autophagy

Autophagy is one of the main mechanisms in the pathophysiology of neurodegenerative disease. The accumulation of autophagic vacuoles (AVs) in affected neurons is responsible for amyloid-β (Aβ) production. Previously, we reported that SUMO1 (small ubiquitin-like modifier 1) increases Aβ levels. In th...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Autophagy
Egile Nagusiak: Cho, Sun-Jung, Yun, Sang-Moon, Jo, Chulman, Lee, Dae-hoon, Choi, Ki Ju, Song, Jae Chun, Park, Sang Ick, Kim, You-Jin, Koh, Young Ho
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2014
Gaiak:
Basic Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502770/
https://ncbi.nlm.nih.gov/pubmed/25484073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.984283
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