EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinase.

Overexpression of a TPA-insensitive PKC member, an atypical protein kinase C (aPKClambda), results in an enhancement of the transcriptional activation of TPA response element (TRE) in cells stimulated with epidermal growth factor (EGF) or platelet-derived growth factor (PDGF). EGF or PDGF also cause...

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Détails bibliographiques
Auteurs principaux: Akimoto, K, Takahashi, R, Moriya, S, Nishioka, N, Takayanagi, J, Kimura, K, Fukui, Y, Osada, S i, Mizuno, K, Hirai, S i, Kazlauskas, A, Ohno, S
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC450277/
https://ncbi.nlm.nih.gov/pubmed/8631300
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