Modulation of deregulated chaperone-mediated autophagy by a phosphopeptide

The P140 peptide, a 21-mer linear peptide (sequence 131–151) generated from the spliceosomal SNRNP70/U1–70K protein, contains a phosphoserine residue at position 140. It significantly ameliorates clinical manifestations in autoimmune patients with systemic lupus erythematosus and enhances survival i...

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Bibliographic Details
Published in:Autophagy
Main Authors: Macri, Christophe, Wang, Fengjuan, Tasset, Inmaculada, Schall, Nicolas, Page, Nicolas, Briand, Jean-Paul, Cuervo, Ana Maria, Muller, Sylviane
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
Subjects:
Basic Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502742/
https://ncbi.nlm.nih.gov/pubmed/25719862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1017179
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