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How the Atg1 complex assembles to initiate autophagy

The Atg1 complex, comprising Atg1, Atg13, Atg17, Atg29, and Atg31, is a key initiator of autophagy. The Atg17-Atg31-Atg29 subcomplex is constitutively present at the phagophore assembly site (PAS), while Atg1 and Atg13 join the complex when autophagy is triggered by starvation or other signals. We s...

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Bibliographic Details
Published in:Autophagy
Main Authors: Davies, Christopher W, Stjepanovic, Goran, Hurley, James H
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502730/
https://ncbi.nlm.nih.gov/pubmed/25700739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15548627.2014.984281
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