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RNA-DNA hybrid formation at the human mitochondrial heavy-strand origin ceases at replication start sites: an implication for RNA-DNA hybrids serving as primers.

Critical elements of a mammalian mitochondrial DNA heavy-strand replication origin include a promoter and three downstream conserved sequence blocks (CSBIII, CSBII and CSBI). We found recently that a stable and persistent RNA-DNA hybrid forms during in vitro transcription at Saccharomyces cerevisiae...

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Bibliografiske detaljer
Main Authors: Xu, B, Clayton, D A
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC450256/
https://ncbi.nlm.nih.gov/pubmed/8670814
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