Tumor necrosis factor-alpha induces VCAM-1-mediated inflammation via c-Src-dependent transactivation of EGF receptors in human cardiac fibroblasts

BACKGROUND: Tumor necrosis factor-α (TNF-α) is a proinflammatory cytokine and elevated in the regions of tissue injury and inflammatory diseases. The deleterious effects of TNF-α on fibroblasts may aggravate heart inflammation mediated through the up-regulation of adhesion molecules such as vascular...

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發表在:J Biomed Sci
Main Authors: Lin, Chih-Chung, Pan, Chih-Shuo, Wang, Chen-Yu, Liu, Shiau-Wen, Hsiao, Li-Der, Yang, Chuen-Mao
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502472/
https://ncbi.nlm.nih.gov/pubmed/26173590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-015-0165-8
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