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The 'destruction box' of cyclin A allows B-type cyclins to be ubiquitinated, but not efficiently destroyed.

The destruction of mitotic cyclins by programmed proteolysis at the end of mitosis is an important element in cell cycle control. This proteolysis depends on a conserved motif of nine residues known as the 'destruction box', which is located 40-50 residues from the N-terminus. The sequence...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Klotzbücher, A, Stewart, E, Harrison, D, Hunt, T
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC450246/
https://ncbi.nlm.nih.gov/pubmed/8670806
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