The prolactin gene is expressed in the hypothalamic-neurohypophyseal system and the protein is processed into a 14-kDa fragment with activity like 16-kDa prolactin.

The 23-kDa form of prolactin (PRL) has been proposed to function as both a mature hormone and a prohormone precursor for different uniquely bioactive forms of the molecule. We have shown that the 16-kDa N-terminal fragment of PRL (16K PRL) inhibits angiogenesis via a specific receptor. In addition,...

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Bibliographic Details
Main Authors: Clapp, C, Torner, L, Gutiérrez-Ospina, G, Alcántara, E, López-Gómez, F J, Nagano, M, Kelly, P A, Mejía, S, Morales, M A, Martínez de la Escalera, G
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC45024/
https://ncbi.nlm.nih.gov/pubmed/7937959
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