Calnexin and calreticulin promote folding, delay oligomerization and suppress degradation of influenza hemagglutinin in microsomes.

Calnexin (CNX) and calreticulin (CRT) are molecular chaperones that bind preferentially to monoglucosylated trimming intermediates of glycoproteins in the endoplasmic reticulum. To determine their role in the maturation of newly synthesized glycoproteins, we analyzed the folding and trimerization of...

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Bibliographic Details
Published in:EMBO J
Main Authors: Hebert, D N, Foellmer, B, Helenius, A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1996
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450237/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8670797/
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