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P19 Cells Overexpressing Lhx1 Differentiate into the Definitive Endoderm by Recapitulating an Embryonic Developmental Pathway

BACKGROUND: Epiblasts occur at the last pluripotent stage of embryonic development and are important in elucidating how the three germ layers are formed. However, little is known of the molecular mechanisms of their development. We have shown that LIM homeobox 1 (Lhx1) was involved in epiblast devel...

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Detalhes bibliográficos
Publicado no:Yonago Acta Med
Main Authors: Hasegawa, Akira, Shirayoshi, Yasuaki
Formato: Artigo
Idioma:Inglês
Publicado em: Tottori University Faculty of Medicine 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502295/
https://ncbi.nlm.nih.gov/pubmed/26190893
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