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Developmentally programmed DNA deletion in Tetrahymena thermophila by a transposition-like reaction pathway.

We provide a molecular description of key intermediates in the deletion of two internal eliminated sequences (IES elements), the M and R regions, during macronuclear development in Tetrahymena thermophila. Using a variety of PCR-based methods in vivo, double-strand breaks are detected that are gener...

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Publicat a:EMBO J
Autors principals: Saveliev, S V, Cox, M M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450224/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8654384/
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