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Adeno-associated virus mediated interferon-gamma inhibits the progression of hepatic fibrosis in vitro and in vivo

AIM: To investigate the effects of adeno-associated virus (AAV) mediated expression of human interferon-γ for gene therapy in experimental hepatic fibrosis in vitro and in vivo. METHODS: We constructed the recombinant AAV encoding human INF-γ (rAAV- INF-γ) and took the primary rat hepatic stellate c...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Chen, Miao, Wang, Guang-Ji, Diao, Yong, Xu, Rui-An, Xie, Hai-Tang, Li, Xin-Yan, Sun, Jian-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502101/
https://ncbi.nlm.nih.gov/pubmed/15996030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i26.4045
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