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HLA-DR4-associated T- and B-cell responses to specific determinants on the IA-2 autoantigen in Type 1 diabetes
Autoantibodies to IA-2 in Type 1 diabetes are associated with HLA-DR4, suggesting influences of HLA-DR4 restricted T-cells on IA-2-specific B-cell responses. The aim of this study was to investigate possible T-B-cell collaboration by determining whether autoantibodies to IA-2 epitopes are associated...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4502080/ https://ncbi.nlm.nih.gov/pubmed/25225671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301902 |
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