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Celecoxib influences steroid sulfonation catalyzed by human recombinant sulfotransferase 2A1

Celecoxib has been reported to switch the human SULT2A1-catalyzed sulfonation of 17βestradiol (17β-E2) from the 3- to the 17-position. The effects of celecoxib on the sulfonation of selected steroids catalyzed by human SULT2A1 were assessed through in vitro and in silico studies. Celecoxib inhibited...

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Detalhes bibliográficos
Publicado no:J Steroid Biochem Mol Biol
Main Authors: Ambadapadi, Sriram, Wang, Peter L., Palii, Sergiu P., James, Margaret O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501872/
https://ncbi.nlm.nih.gov/pubmed/25960318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2015.05.003
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