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Synaptic dysregulation in a human iPS cell model of mental disorders

Dysregulated neurodevelopment with altered structural and functional connectivity is believed to underlie many neuropsychiatric disorders(1), and ‘a disease of synapses’ is the major hypothesis for the biological basis of schizophrenia(2). Although this hypothesis has gained indirect support from hu...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Wen, Zhexing, Nguyen, Ha Nam, Guo, Ziyuan, Lalli, Matthew A., Wang, Xinyuan, Su, Yijing, Kim, Nam-Shik, Yoon, Ki-Jun, Shin, Jaehoon, Zhang, Ce, Makri, Georgia, Nauen, David, Yu, Huimei, Guzman, Elmer, Chiang, Cheng-Hsuan, Yoritomo, Nadine, Kaibuchi, Kozo, Zou, Jizhong, Christian, Kimberly M., Cheng, Linzhao, Ross, Christopher A., Margolis, Russell L., Chen, Gong, Kosik, Kenneth S., Song, Hongjun, Ming, Guo-li
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501856/
https://ncbi.nlm.nih.gov/pubmed/25132547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13716
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