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Interferon at the crossroads of allergy and viral infections

IFN-α/β was first described as a potent inhibitor of viral replication, but it is now appreciated that IFN signaling plays a pleiotropic role in regulating peripheral T cell functions. Recently, IFN-α/β was shown to block human Th2 development by suppressing the transcription factor GATA3. This effe...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Gonzales-van Horn, Sarah R., Farrar, J. David
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501675/
https://ncbi.nlm.nih.gov/pubmed/26026068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3RU0315-099R
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