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The structure of the human mitochondrial ribosome

The highly divergent ribosomes of human mitochondria (mitoribosomes) synthesize 13 essential proteins of oxidative phosphorylation complexes. We have determined the structure of the intact mitoribosome to 3.5 angstrom resolution by single-particle electron cryo-microscopy. It reveals 80 extensively...

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Udgivet i:Science
Main Authors: Amunts, Alexey, Brown, Alan, Toots, Jaan, Scheres, Sjors H. W., Ramakrishnan, V.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501431/
https://ncbi.nlm.nih.gov/pubmed/25838379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa1193
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