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Constellation Pharmacology: A new paradigm for drug discovery
Constellation Pharmacology is a cell-based high-content phenotypic-screening platform that utilizes subtype-selective pharmacological agents to elucidate the cell-specific combinations (“constellations”) of key signaling proteins that define specific cell types. Heterogeneous populations of native c...
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Pubblicato in: | Annu Rev Pharmacol Toxicol |
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Autori principali: | , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4501256/ https://ncbi.nlm.nih.gov/pubmed/25562646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010814-124551 |
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