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Constellation Pharmacology: A new paradigm for drug discovery

Constellation Pharmacology is a cell-based high-content phenotypic-screening platform that utilizes subtype-selective pharmacological agents to elucidate the cell-specific combinations (“constellations”) of key signaling proteins that define specific cell types. Heterogeneous populations of native c...

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Détails bibliographiques
Publié dans:Annu Rev Pharmacol Toxicol
Auteurs principaux: Teichert, Russell W., Schmidt, Eric W., Olivera, Baldomero M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4501256/
https://ncbi.nlm.nih.gov/pubmed/25562646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010814-124551
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