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Restriction by EcoKI is enhanced by co-operative interactions between target sequences and is dependent on DEAD box motifs.

One subunit of both type I and type III restriction and modification enzymes contains motifs characteristic of DEAD box proteins, which implies that these enzymes may be DNA helicases. This subunit is essential for restriction, but not modification. The current model for restriction by both types of...

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Bibliographic Details
Published in:EMBO J
Main Authors: Webb, J L, King, G, Ternent, D, Titheradge, A J, Murray, N E
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450119/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617247/
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