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Transfer RNA-dependent cognate amino acid recognition by an aminoacyl-tRNA synthetase.

An investigation of the role of tRNA in the catalysis of aminoacylation of Escherichia coli glutaminyl-tRNA synthetase (GlnRS) has revealed that the accuracy of specific interactions between GlnRS and tRNAGln determines amino acid affinity. Mutations in GlnRS at D235, which makes contacts with nucle...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Hong, K W, Ibba, M, Weygand-Durasevic, I, Rogers, M J, Thomann, H U, Söll, D
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450117/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617245/
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