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The interleukin-7 receptor alpha chain transmits distinct signals for proliferation and differentiation during B lymphopoiesis.

The interleukin 7 receptor (IL7R), which contains a unique alpha chain and a gamma chain shared by other cytokine receptors, is indispensable for normal lymphocyte development. The basis for this role is poorly understood. Here we show that the IL7R alpha chain not only causes progenitors to prolife...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Corcoran, A E, Smart, F M, Cowling, R J, Crompton, T, Owen, M J, Venkitaraman, A R
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450111/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617239/
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