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The conserved amino-terminal domain of hSRP1 alpha is essential for nuclear protein import.

Nuclear proteins are targeted through the nuclear pore complex (NPC) in an energy-dependent reaction. The import reaction is mediated by nuclear localization sequences (NLS) in the substrate which are recognized by heterodimeric cytoplasmic receptors. hSRP1 alpha is an NLS-binding subunit of the hum...

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Bibliografski detalji
Izdano u:EMBO J
Glavni autori: Weis, K, Ryder, U, Lamond, A I
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 1996
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450098/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8617227/
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