Potential of N-acetylated-para-aminosalicylic Acid to Accelerate Manganese Enhancement Decline for Long-term MEMRI in Rodent Brain

BACKGROUND: Manganese (Mn(2+))-enhanced MRI (MEMRI) is a valuable imaging tool to study brain structure and function in normal and diseased small animals. The brain retention of Mn(2+) is relatively long with a half-life (t(1/2)) of 51 to 74 days causing a slow decline of MRI signal enhancement foll...

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Publicado en:J Neurosci Methods
Main Authors: Bade, Aditya N, Zhou, Biyun, McMillan, JoEllyn, Narayanasamy, Prabagaran, Veerubhotla, Ram, Gendelman, Howard E, Boska, Michael D, Liu, Yutong
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500662/
https://ncbi.nlm.nih.gov/pubmed/26004847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2015.05.013
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