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Mucin 1 Regulates Cox-2 Gene in Pancreatic Cancer
OBJECTIVE: Eighty percent of pancreatic ductal adenocarcinomas (PDAs) overexpress mucin 1 (MUC1), a transmembrane mucin glycoprotein. MUC1(high) PDA patients also express high levels of cyclooxygenase 2 (COX-2) and show poor prognosis. The cytoplasmic tail of MUC1 (MUC1-CT) partakes in oncogenic sig...
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| Publicado no: | Pancreas |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500655/ https://ncbi.nlm.nih.gov/pubmed/26035123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000371 |
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