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Michael Additions of Highly Basic Enolates to ortho-Quinone Methides

[Image: see text] A protocol by which ketone or ester enolates and ortho-quinone methides (o-QMs) are generated in situ in a single reaction flask from silylated precursors under the action of anhydrous fluoride is reported. The reaction partners are joined to give a variety of β-(2-hydroxyphenyl)-c...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Lewis, Robert S., Garza, Christopher J., Dang, Ann T., Pedro, Te Kie A., Chain, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500648/
https://ncbi.nlm.nih.gov/pubmed/25906358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b00972
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