The transition of pre-BI to pre-BII cells is dependent on the VH structure of the mu/surrogate L chain receptor.
We have demonstrated previously that the majority ( > 90%) of VH12 B cells are absent from the adult peripheral repertoire, and that most that remain have the fourth position at the D-J function (designated 10/G4). We report here that most VH 12-expressing pre-B cells are lost during the transition...
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| Publicado no: | EMBO J |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450060/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8612575/ |
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