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Optimum 3D Matrix Stiffness for Maintenance of Cancer Stem Cells Is Dependent on Tissue Origin of Cancer Cells

INTRODUCTION: The growth and expression of cancer stem cells (CSCs) depend on many factors in the tumor microenvironment. The objective of this work was to investigate the effect of cancer cells’ tissue origin on the optimum matrix stiffness for CSC growth and marker expression in a model polyethyle...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jabbari, Esmaiel, Sarvestani, Samaneh K., Daneshian, Leily, Moeinzadeh, Seyedsina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500566/
https://ncbi.nlm.nih.gov/pubmed/26168187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132377
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