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Association of DNA Damage Repair Gene Polymorphisms hOGG1, XRCC1and p53 with Sickle Cell Disease Patients in India

BACKGROUND: Oxidative stress constitutes one of the significant cause of vaso-occlusive clinical episodes in sickle cell disease (SCD) patients. It brings about the generation of reactive oxygen species and consequent damage to DNA. DNA damage repair genes such as hOGG1, XRCC1 and p53 play an import...

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Bibliografske podrobnosti
izdano v:Mediterr J Hematol Infect Dis
Glavni avtor: Nishank, Sudhansu Sekhar
Format: Artigo
Jezik:Inglês
Izdano: Università Cattolica del Sacro Cuore 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500474/
https://ncbi.nlm.nih.gov/pubmed/26185611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4084/MJHID.2015.046
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