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The C-terminal domain of eukaryotic protein synthesis initiation factor (eIF) 4G is sufficient to support cap-independent translation in the absence of eIF4E.

The foot and mouth disease virus, a picornavirus, encodes two forms of a cysteine proteinase (leader or L protease) that bisects the EIF4G polypeptide of the initiation factor complex eIF4F into N-terminal (Nt) and C-terminal (Ct) domains. Previously we showed that, although in vitro cleavage of the...

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Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Ohlmann, T, Rau, M, Pain, V M, Morley, S J
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1996
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8635470/
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