3-Iodothyroacetic acid lacks thermoregulatory and cardiovascular effects in vivo

BACKGROUND AND PURPOSE: 3-Iodothyronamine (3-T(1)AM) is an endogenous thyroid hormone derivative reported to induce strong hypothermia and bradycardia within minutes upon injection in rodents. Although 3-T(1)AM is rapidly converted to several other metabolites in vivo, these strong pharmacological r...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Hoefig, Carolin S, Jacobi, Simon F, Warner, Amy, Harder, Lisbeth, Schanze, Nancy, Vennström, Björn, Mittag, Jens
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
Teme:
Research Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500376/
https://ncbi.nlm.nih.gov/pubmed/25765843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13131
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