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Selected ginsenosides of the protopanaxdiol series are novel positive allosteric modulators of P2X7 receptors

BACKGROUND AND PURPOSE: The P2X7 receptor is an ATP-gated ion channel predominantly expressed in immune cells and plays a key role in inflammatory processes. Ginseng is a well-known Chinese herb with both pro- and anti-inflammatory properties and many of its actions have been ascribed to constituent...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Helliwell, R M, ShioukHuey, C O, Dhuna, K, Molero, J C, Ye, J-M, Xue, C C, Stokes, L
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Ltd 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500369/
https://ncbi.nlm.nih.gov/pubmed/25752193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13123
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