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Pub1 acts as an E6-AP-like protein ubiquitiin ligase in the degradation of cdc25.

The level of the mitotic activating tyrosine phosphatase cdc25 is regulated by both transcriptional and post-transcriptional mechanisms in the fission yeast Schizosaccharomyces pombe. We have found that cdc25 is ubiquitinated and have cloned pub1, a gene which regulates this event. Pub1 contains a r...

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Detalhes bibliográficos
Main Authors: Nefsky, B, Beach, D
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC450033/
https://ncbi.nlm.nih.gov/pubmed/8635463
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