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Functional rescue of mutant V2 vasopressin receptors causing nephrogenic diabetes insipidus by a co-expressed receptor polypeptide.

Inactivating mutations in distinct G protein-coupled receptors (GPCRs) are currently being identified as the cause of a steadily growing number of human diseases. Based on previous studies showing that GPCRs are assembled from multiple independently stable folding units, we speculated that such muta...

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Vydáno v:EMBO J
Hlavní autoři: Schoneberg, T, Yun, J, Wenkert, D, Wess, J
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1996
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450031/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8635461/
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