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Multiple SH3 domain interactions regulate NADPH oxidase assembly in whole cells.

Src homology 3 (SH3) domains mediate specific protein-protein interactions crucial for signal transduction and protein subcellular localization. Upon phagocyte stimulation, two SH3 domain-containing cytosolic components of the NADPH oxidase, p47phox and p67phox, are recruited to the membrane where t...

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Bibliographic Details
Published in:EMBO J
Main Authors: de Mendez, I, Adams, A G, Sokolic, R A, Malech, H L, Leto, T L
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 1996
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC450022/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8635453/
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