Cellular immune correlates analysis of an HIV-1 preexposure prophylaxis trial

HIV-1–specific T-cell responses in exposed seronegative subjects suggest that a viral breach of the exposure site is more common than current transmission rates would suggest and that host immunity can extinguish subsequent infection foci. The Preexposure Prophylaxis Initiative (iPrEx) chemoprophyla...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Kuebler, Peter J., Mehrotra, Megha L., McConnell, J. Jeff, Holditch, Sara J., Shaw, Brian I., Tarosso, Leandro F., Leadabrand, Kaitlyn S., Milush, Jeffrey M., York, Vanessa A., Raposo, Rui André Saraiva, Cheng, Rex G., Eriksson, Emily M., McMahan, Vanessa, Glidden, David V., Shiboski, Stephen, Grant, Robert M., Nixon, Douglas F., Kallás, Esper G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500209/
https://ncbi.nlm.nih.gov/pubmed/26100867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501443112
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